AMSBIO has announced a new range of AAV reference materials of full capsids and empty capsids of 6 different serotypes.
Critical to enable meaningful comparisons between research studies and clinical trials, these well-characterized reference standards are extensively quality analyzed with molecular based assays and transmission electron microscope.
Gene therapy researchers have long expressed the importance of well characterized AAV reference materials. Recombinant adeno-associated virus (rAAV) is a widely used gene delivery tool for research and clinical applications. Following the US Federal Drug Administration gene therapy CMC guidance published in January 2020, commercially sourced, well-characterized AAV reference materials are one of the cited reference materials for gene therapy.
AMSBIO’s AAV reference materials (full capsids) with accurate vector genome concentration can be used in qPCR-based vector genome quantification. Additionally, these AAV reference materials are well characterized for full-to-empty capsid ratio. AAV reference materials are available from AMSBIO in AAV1, AAV2, AAV5, AAV6, AAV8 and AAV9 serotypes.
Adeno-Associated Virus are also known to produce empty particles without payloads. These high purity, quality certified AAV empty capsids reference materials can be used as controls and standards in assays, including HPLC and ELISA, AMSBIO offer these AAV empty capsid reference materials in AAV1, AAV2, AAV5, AAV6, AAV8 and AAV9 serotypes.
For further information on well characterized, high quality AAV reference materials please visit https://www.amsbio.com/aav-reference-standards/ or contact AMSBIO on +44-1235-828200 / +1-617-945-5033 / [email protected].
Founded in 1987, AMS Biotechnology (AMSBIO) is recognized today as a leading transatlantic company contributing to the acceleration of discovery through the provision of cutting-edge life science technology, products and services for research and development in the medical, nutrition, cosmetics and energy industries. AMSBIO has in-depth expertise in extracellular matrices to provide elegant solutions for studying cell motility, migration, invasion and proliferation. This expertise in cell culture and the ECM allows AMSBIO to partner with clients in tailoring cell systems to enhance organoid and spheroid screening outcomes using a variety of 3D culture systems, including organ-on-a-chip microfluidics. For drug discovery research, AMSBIO offers assays, recombinant proteins and cell lines. Drawing upon a huge and comprehensive biorepository, AMSBIO is widely recognised as a leading provider of high-quality tissue specimens (including custom procurement) from both human and animal tissues. The company provides unique clinical grade products for stem cell and cell therapy applications these include high quality solutions for viral delivery (lentivirus, adenovirus and adeno-associated virus) in addition to GMP cryopreservation technology.
